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entry into target cells is also impaired2 and less T3 is formed locally, with low tissue concentrations of T3 and T4.3. A low thyroid level can cause symptoms of fatigue, weakness, lethargy, weight gain, depression, memory problems, constipation,

dry skin, intolerance to cold. Dr Obuobie and Dr Jones (April 2003 JRSM1) attribute the hyperthyroidism with low serum thyroid hormone concentrations

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